Sodium phenylbutyrate, a drug prescribed until now for patients with alterations in the urea cycle, eases the fusion of proteins responsible for neuron connections, thus increasing the learning capacity of the mice involved.
© AFP/File Fred TanneauFebruary 19, 2009, (Sawf News) - Sodium phenylbutyrate, a drug prescribed until now for patients with alterations in the urea cycle, eases the fusion of proteins responsible for neuron connections, thus increasing the learning capacity of the mice involved.
The new discovery offers promising perspectives for the treatment of Alzheimer's Disease and other related dementias.
In addition, these findings provide a new alternative to the drugs that are currently available for fighting this devastating disease, explained Dr. Ana García-Osta, a researcher from the Department of Neurosciences and the principal author of this project.
The research team is currently focused on discovering the acting mechanism in this drug. As the drug is now clinically available and well tolerated, the confirmation of its therapeutic affectivity in humans could be applied to Alzheimer's in a shorter period of time than other drugs being studied.
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